Description

Cederholm et al reported a model for predicting the 5-year risk of cardiovascular disease for a patient with type 1 diabetes. This can help to identify a patient who may require management of cardiovascular disease. The authors are from Uppsala University and the University of Gothenburg.


Patient selection: Type 1 diabetes in Sweden from 30 to 65 years of age

 

Parameters:

(1) duration of diabetes in years

(2) onset age of diabetes in years (current age minus duration)

(3) total cholesterol to HDL cholesterol ratio

(4) hemoglobin A1c in percent

(5) systolic blood pressure in mm Hg

(6) smoker (>=1 cigarettes per day; use of pipe), current or stopped within past 3 months

(7) macroalbuminuria

(8) previous cardiovascular disease

 

Parameter

Finding

Points

duration of diabetes

 

0.08426 * ((years) - 28.014)

onset age

 

0.04742 * ((age)-(duration)-16.601)

TC/HDLC ratio

 

0.80050 * (LN(ratio) - 1.1470)

hemoglobin A1c

 

1.27275 * (LN(HgbA1c) - 2.0605)

systolic blood pressure

 

1.20050 * (LN(SBP) - 4.8598)

smoker

no

0.56688 (0 - 0.1483)

 

yes

0.56688 (1 - 0.1483)

macroalbuminuria

no

0.41995 * (0-0.1237)

 

yes

0.41995 * (1-0.1237)

history of previous cardiovascular disease

no

1.25506 * (0-0.0612)

 

yes

1.25506 * (1-0.0612)

 

X =

= SUM(points for all of the parameters)

 

5-year risk of cardiovascular disease =

= 1 - 0.97136^EXP(X)


To read more or access our algorithms and calculators, please log in or register.