 ### Description

In diabetics the mean daily plasma glucose can be estimated from the glycohemoglobin level.

Based on Total Glycohemoglobin (Wallach)

estimated mean daily plasma glucose (mg/dL) =

= (10 * ((total glycohemoglobin A1 level in percent) + 4)) =

= (10 * (total glycohemoglobin A1 level in percent)) + 40

where:

• total glycohemoglobin A1 = A1a + A1b + A1c

• normal total glycohemoglobin: 4-8%

• The equation is applicable for total glycohemoglobin A1 levels between 4-20%.

Based on Hemoglobin A1c Alone

 Hemoglobin A1c in Percent Whole Blood Glucose in mg/dL 6% 120 7% 150 8% 180 9% 210 10% 240 11% 270 12% 300 13% 330 14% 360

If this data is modeled in JMP:

whole blood glucose in mg/dL =

= (30 * (percent HgbA1c as a whole number)) - 60

The formulae recommended by the ADA are based on the A1c-Derived Daily Glucose (ASAG) study:

estimated average glucose in mg/dL =

= (28.7 * (percent hemoglobin A1c)) - 46.7

estimated average glucose in mmol/L =

= (1.59 * (percent hemoglobin A1c)) - 2.59