Description

In diabetics the mean daily plasma glucose can be estimated from the glycohemoglobin level.


 

Based on Total Glycohemoglobin (Wallach)

 

estimated mean daily plasma glucose (mg/dL) =

= (10 * ((total glycohemoglobin A1 level in percent) + 4)) =

= (10 * (total glycohemoglobin A1 level in percent)) + 40

 

where:

• total glycohemoglobin A1 = A1a + A1b + A1c

• normal total glycohemoglobin: 4-8%

• The equation is applicable for total glycohemoglobin A1 levels between 4-20%.

 

Based on Hemoglobin A1c Alone

 

Hemoglobin A1c in Percent

Whole Blood Glucose in mg/dL

6%

120

7%

150

8%

180

9%

210

10%

240

11%

270

12%

300

13%

330

14%

360

 

If this data is modeled in JMP:

 

whole blood glucose in mg/dL =

= (30 * (percent HgbA1c as a whole number)) - 60

 

American Diabetes Association (ADA) Equations

 

The formulae recommended by the ADA are based on the A1c-Derived Daily Glucose (ASAG) study:

 

estimated average glucose in mg/dL =

= (28.7 * (percent hemoglobin A1c)) - 46.7

 

estimated average glucose in mmol/L =

= (1.59 * (percent hemoglobin A1c)) - 2.59

 


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