The corrected serum sodium level should be calculated in nonketotic hyperosmolar coma. Apparent mild hyponatremia occurring with very high glucose levels may actually represent hypernatremia.

corrected sodium level in mEq/L = corrected sodium level in mmol/L =

= (measured sodium in mEq/L) + ((variable) * (glucose in mg/dL) /100)



• variable = a value from 1.3 to 1.6, most often 1.6. This corresponds to the 1.6 mmol/L change in serum sodium for every 100 mg/dL of glucose.

• sodium in mmol/L = mEq/L


Another equation (Wall) is used when the serum glucose is > 200 mg/dL


corrected sodium level in mmol/L =

= (measured sodium in mmol/L) + (0.016 * ((measured glucose in mg/dL) – 100))



• 0.016 is equivalent to the previous equation's (variable) / 100.

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