Description

A BIDO regimen (bedtime insulin, daytime oral agent) may be used by a patient who is still hyperglycemic while receiving an oral hypoglycemic agent.


 

Patient selection: mild hyperglycemia while on maximal dose of an oral hypoglycemic agent AND preference to avoid a full insulin dosage regimen

 

Benefits:

(1) minimum number of fingersticks per day

(2) minimum number of insulin injections

 

Parameters:

(1) fasting glucose level in mg/dL for 2 days in a row

(2) body habitus (lean vs obese)

 

Insulin used: NPH or glarcine

 

The initial bedtime dose for a lean patient is 8 to 10 IU insulin. while for an obese patient it is 14 to 16 units.

 

Fasting Glucose (for 2 days in a row)

Lean Patient

Obese Patient

< 150 mg/dL on both days

0

0

>= 200 on both days

+2 units

2 times lean

otherwise

+1 unit

2 times lean

 

Requirements:

(1) The fasting blood glucose values are accurate.

(2) The patient keeps accurate records and submits them to the provider regularly.

(3) The patient understands and can follow the algorithm.

 


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