Description

Patients who have received an organ transplant are at increased risk for developing new-onset diabetes mellitus.


 

Risk factors for new-onset diabetes mellitus after receiving an organ transplant:

(1) ethnic group (Black or Hispanic)

(2) family history of diabetes mellitus, in first degree relatives

(3) obesity

(4) history of glucose intolerance or gestational diabetes

(5) viral hepatitis C infection

(6) age > 40 years

(7) if renal transplant, a cadaver kidney

(8) type of immunosuppressive therapy (tacrolimus > cyclosporine, high dose corticosteroid therapy)

(9) dyslipidemia

 

Parameter

Finding

Points

ethnic group

Black

1

 

Hispanic

1

 

other

0

family history of diabetes

absent

0

 

present

1

body weight

not obese

0

 

obese

1

history of glucose intolerance or gestational diabetes

absent

0

 

present

1

viral hepatitis C

absent

0

 

present

1

age

<= 40 years of age

0

 

> 40 years of age

1

immunosuppressive therapy

tacrolimus

1

 

other

0

high dose corticosteroid therapy

no

0

 

yes

1

dysplipidemia

absent

0

 

present

1

source of organ (if renal transplant)

cadaver

1

 

other

0

 

total number of risk factors =

= SUM(points for all of the parameters)

 

The risk for new-onset diabetes increases as the number of risk factors increase.

 


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