Contraindications & Precautions in Use of Sulfonylurea | Diabetes Mellitus

• have a hypersensitivity to sulfa drugs or sulfonylureas?

• have a history of bone marrow depression following exposure to a sulfonylurea?

• have very few functional islets cells?

• have a history of glyburide-induced hepatitis?

• have a history of chlorpropamide-induced cholestatic jaundice?

• have a history of sulfonylurea-induced porphyria?

• have a history SIADH following therapy with chlorpropamide or tolbutamide?

• develop a disulfiram-like reaction on exposure to alcohol?

• have a history of a phototoxic reaction to a sulfonylurea?