The European Consensus Lupus Activity Measurement (ECLAM)

generalized symptoms

none

0

morning temperature >= 37.5°C not due to infection, OR feeling extraordinary tiredness

0.5

arthritis or arthrlagia

none

0

non-erosive arthritis OR arthralgia in 2 or more peripheral joints

1

cutaneous manifestations

none

0

malar erythema, maculopapular rash, patches, digital ulcers, purpura, urticaria, bullous lesions oral ulcer, OR nasopharyngeal ulcer

0.5

myositis

none

0

elevated muscle enzymes, EMG changes, OR by histologic examination

2

pericarditis

none

0

documented by ECG, rub, pericardial effusion or ultrasound

1

gut manifestations

none

0

gut vasculitis OR peritoneal effusion in the absence of an infective process

2

pulmonary manifestations

none

0

pleural effusion, pneumonitis not due to an infection, OR interstitial disease with dyspnea

1

neuropsychiatric manifestations

none

0

headache, migraine, seizures, stroke, impaired memory, organic brain disease OR psychosis

2

renal manifestations

none

0

proteinuria, any kind of urinary casts, microscopic hematuria, gross hematuria, elevated serum creatinine OR decreased creatinine clearance

0.5

hematologic

none

0

nonhemolytic anemia, hemolytic anemia, leukopenia, lymphopenia OR thrombocytopenia, in the absence of offending drugs

1

ESR

<= 25 mm in first hour by Westergren method

0

> 25 mm in first hour by Westergren method in the absence of any other pathologic process

1

complement

normal

0

reduced plasma C3 and/or CH50

1

if any muco-cutaneous manifestation is new or has worsened since the last observation

1 point

if any renal manifestation is new or has worsened since the last observation

2 points

if C3, C4 or CH50 are significantly less than the last observation

1 point

if the only manifestation is myositis OR neuro-psychiatric OR renal

2 points