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ANA Negative Systemic Lupus Erythematosus (SLE)

Purpose:

To identify a patient with ANA-negative systemic lupus erythematosus (SLE).

Specialty:

Immunology/Rheumatology

Objective:

laboratory tests, severity, prognosis, stage, differential diagnosis and mimics, red flags, disease progression, prevention

ICD-10:

M32

Description:

Most patients with systemic lupus erythematosus (SLE) have elevated titers of antinuclear antibodies (ANA). However, around 10% of patients with SLE have normal titers of ANA, which can result in a delay or mistake in diagnosis.

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