Systemic Lupus Erythematosus Disease Activity Index (SLEDAI)

Has the patient had the recent onset of seizures, unexplained by metabolic, infectious or drug causes?

Has the patient shown psychotic behavior?

Does the patient show altered mental function, with impaired orientation, memory or other intellectual functions?

Does the patient have a visual disturbance, with retinal changes associated with lupus?

Does the patient have a new onset of sensory or motor neuropathy involving cranial nerves?

Does the patient have a severe, persistent headache, unrelieved by narcotic analgesics?

Has the patient had a recent cerebrovascular accident (CVA) or stroke, not due to arteriosclerosis?

Does the patient have skin ulcerations or areas of gangrene?

Does the patient have tender finger nodules, periungual infarctions, or splinter hemorrhages?

Does the patient have biopsy or angiographic evidence of vasculitis?

Number of joints with pain, tenderness, swelling and/or effusion

Does the patient have proximal muscle aching or weakness?

Does the patient have elevated serum creatine phosphokinase or aldolase?

Does the patient have changes in an electromyogram or a biopsy consistent with myositis?

Does the patient have a new onset or recurrence of inflammatory type rash?

Has the patient had a new onset or recurrence of abnormal, patchy or diffuse loss of hair?

Has the patient had a new onset or recurrence of oral or nasal ulcerations?

Has the patient had pleuritic chest pain with pleural rub or effusion, or pleural thickening?

Does the patient have pericardial pain ?

Does the patient have a pericardial rub or effusion?

Does the patient have electrocardiogram or echocardiogram evidence of a pericardial effusion?

Body temperature

Platelet count

WBC count

Are the decrease in blood cell counts due to drugs or toxins?

Current urine protein output

Previous urine protein output

Does the patient have heme-granular or red blood cell casts in the urine sediment?

Number of red blood cells in the urine

Number of white blood cells in the urine

Can the urine findings be explained by stone, infection or other cause?

Does the patient show a decrease in CH50, C3 or C4?

Does the patient show evidence of increased DNA binding by the Farr or other assay?