The Centers for Disease Control (CDC) developed criteria for the diagnosis of perinatal exposure in a child. This is designated by the prefix "E".
Parameters:
(1) child's HIV antibody test
(2) maternal HIV status
Criteria for perinatal exposure:
(1) mother known to be HIV infected during the pregnancy AND HIV antibody status unknown
(2) child < 18 months old when tested for HIV antibody AND HIV antibody test confirmed positive (EIA positive with Western blot or immunofluorescence assay positive)
Possible outcomes on continued followup:
(1) HIV infected (meets criteria for HIV infected, see previous section)
(2) HIV uninfected with seroreversion
Need to exclude:
(1) false positive test for antibody to HIV in mother
(2) false negative test for antibody to HIV in child
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