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CD4 Lymphocyte Count

Purpose: To measure lymphocyte subsets to aid in the management of a patient with HIV infection.

Description

A decrease in the absolute CD4 positive lymphocyte count is associated with the progression to clinical AIDS.


 

Parameters:

(1) absolute lymphocyte count

(2) CD4+ lymphocyte count

 

In children infected with HIV, the level of immunosuppression correlates with the CD4+ lymphocyte count and the percentage CD4+ lymphocyte relative to the total lymphocyte count.

 

percent CD4+ lymphocytes =

= (CD4 lymphocyte count per µL) / (absolute lymphocyte count per µL)

 

Parameter

Age

Finding

Immunosuppression

CD4+ percentage

 

15-24%

moderate

 

 

< 15%

severe

CD4+ per µL

<= 11 months

750 – 1,499 per µL

moderate

 

<= 11 months

< 750 per µL

severe

 

1 – 5 years

500 – 999 per µL

moderate

 

1 – 5 years

< 500 per µL

severe

 

6 – 12 years

200 – 499 per µL

moderate

 

6 – 12 years

< 200 per µL

severe

 

In 2014 the absolute CD4 lymphocyte count was associated with the stage of the disease.

 

< 12 months

1 to 5 Years

>=6 Years

HIV Stage

>= 1,500

>= 1,000

>= 500

1

750 to 1,499

500 to 999

200 to 499

2

< 750

< 500

< 200

3

 


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Specialty

Objective

ICD-10