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Prognostic Score of Mizumoto et al for a Patient with Vertebral Metastases Treated with Radiation Therapy

Purpose: To evaluate a patient with cancer metastatic to the vertebral column after radiation therapy using the prognostic score of Mizumoto et al.

Description

Mizumoto et al developed a prognostic score for patients with metastatic cancer to the vertebral column treated with radiation therapy. This can help to identify patients who may benefit from more aggressive management. The authors are from Shizuoka Cancer Hospital in Japan.


Parameters:

(1) age in years

(2) number of bone metastases

(3) hypercalcemia

(4) history of previous chemotherapy

(5) type of primary tumor

(6) ECOG performance scale

(7) visceral metastases

 

Parameter

Finding

Points

age in years

< 71 years

0

 

>= 71 years

1

number of bone metastases

1

0

 

multiple

1

hypercalcemia

absent

0

 

present

2

history of previous chemotherapy

no

0

 

yes

2

type of primary tumor

favorable (breast, prostate, malignant lymphoma, non-anaplastic thyroid carcinoma)

0

 

unfavorable

3

ECOG performance scale

0,1 or 2

0

 

3 or 4

3

visceral metastases

absent

0

 

present

2

 

total score =

= SUM(points for all 7 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 14

• The higher the score the worse the survival.

 

Total Score

Prognostic Group

Mean Median Survival

0 to 4

A

27 months

5 to 9

B

5 months

10 to 14

C

1.8 months

 


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Specialty

Objective

ICD-10