Montalban et al reported a prognostic index for patients with splenic marginal zone lymphoma. The acronym is HPLL for its parameters. The authors are from multiple institutions in Spain and Italy.
Patient selection: splenic marginal zone lymphoma
NOTE: The author subsequently reported a prognostic score using the same parameters.
Parameters:
(1) hemoglobin in g/L (H)
(2) platelet count in 10^9/L (P)
(3) serum LDH in U/L relative to upper limit of normal (L)
(4) extrahilar lymphadenopathy (L)
Parameter
Finding
Points
hemoglobin
0.02 * (hemoglobin)
platelet count
0.006 * (count)
serum LDH
<= ULN
0
> ULN
-1
extrahilar lymphadenopathy
absent
0
present
-1
HPLL prognostic index =
= SUM(points for all 4 parameters)
HPLL PI
Risk Group
5-Year Lymphoma Specific Survival (Derivation Cohort)
>= 2.6
low risk
94%
0.9 to 2.59
intermediate risk
78%
< 0.9
high risk
69%
To read more or access our algorithms and calculators, please log in or register.
