The Follicular Lymphoma International Prognostic Index (FLIPI) was developed for determining prognosis in a patient with follicular lymphoma. This is related to the International Prognostic Index for non-Hodgkin's lymphoma.
Parameters:
(1) age of the patient in years
(2) Ann Arbor stage of the lymphoma
(3) serum LDH
(4) hemoglobin
(5) number of involved nodal sites
Parameter |
Finding |
Points |
---|---|---|
age in years |
< 60 years |
0 |
|
>= 60 years |
1 |
Ann Arbor stage |
I or II |
0 |
|
III or IV |
1 |
serum LDH |
<= upper limit of normal |
0 |
|
> upper limit of normal |
1 |
hemoglobin |
>= 12 g/dL |
0 |
|
< 12 g/dL |
1 |
number of involved nodal sites |
<= 5 |
0 |
|
> 5 |
1 |
FLIPI =
= SUM(points for all 5 parameters)
Interpretation:
• minimum index: 0
• maximum index: 5
• The higher the index the more aggressive the disease and the worse the prognosis/
FLIPI |
Prognosis |
Overall Survival at 5 Years |
---|---|---|
0 or 1 |
good |
88% |
2 |
intermediate |
78% |
3 to 5 |
poor |
55% |
from Figure in Leonard
Purpose: To determine the prognosis for a patient with a follicular lymphoma using the Follicular Lymphoma International Prognostic Index (FLIPI).
Specialty: Hematology Oncology
Objective: severity, prognosis, stage
ICD-10: C82,