Bansal et al reported a model for predicting 5-year risk of death without end-stage renal disease (ESRD) in an older adult with chronic kidney disease (CKD). This can help guide management of the kidney disease in light of comorbidities. The authors are from multiple institutions in the United States.
Patient selection: age >= 70 years with CKD (eGFR < 60 mL per min per 1.73 square m)
Outcome: 5-year mortality without ESRD
Parameters:
(1) age in years
(2) sex
(3) race
(4) eGFR in mL per min per 1.73 square meter
(5) urine albumin to creatinine ratio in mg/g
(6) diabetes mellitus
(7) smoking history
(8) history of heart failure
(9) history of stroke
Parameter |
Finding |
Points |
age in years |
70 to 74 years |
0 |
|
75 to 79 years |
1 |
|
80 to 84 years |
2 |
|
>= 85 years |
4 |
sex |
female |
0 |
|
male |
1 |
race |
Black |
0 |
|
White |
1 |
eGFR |
50 to 59 |
0 |
|
40 to 49 |
1 |
|
30 to 39 |
2 |
|
< 30 |
4 |
urine albumin to creatinine ratio |
< 30 mg/g |
0 |
|
>= 30 mg/g |
1 |
diabetes |
no |
0 |
|
yes |
1 |
smoking |
never |
0 |
|
former |
1 |
|
current |
2 |
history of heart failure |
no |
0 |
|
yes |
2 |
history of stroke |
no |
0 |
|
yes |
1 |
total score =
= SUM(points for all 9 parameters)
Interpretation:
• minimum score: 0
• maximum score: 17
• The risk of mortality increases with the score.
Total Score |
Risk of 5-Year Mortality |
0 |
3.9% |
1 |
5.9% |
2 |
8.8% |
3 |
13.2% |
4 |
19.4% |
5 |
28% |
6 |
40% |
7 |
54% |
8 |
69% |
9 |
84% |
>= 10 |
94% |
Performance:
• The area under the ROC curve was 0.69.
Purpose: To perdict the 5-year mortality rate without end-stage renal disease (ESRD) for an older adult with chronic kidney disease using the model of Bansal et al.
Specialty: Nephrology
Objective: risk factors
ICD-10: N17-N19,