Description

Bansal et al reported a model for predicting 5-year risk of death without end-stage renal disease (ESRD) in an older adult with chronic kidney disease (CKD). This can help guide management of the kidney disease in light of comorbidities. The authors are from multiple institutions in the United States.


Patient selection: age >= 70 years with CKD (eGFR < 60 mL per min per 1.73 square m)

 

Outcome: 5-year mortality without ESRD

 

Parameters:

(1) age in years

(2) sex

(3) race

(4) eGFR in mL per min per 1.73 square meter

(5) urine albumin to creatinine ratio in mg/g

(6) diabetes mellitus

(7) smoking history

(8) history of heart failure

(9) history of stroke

 

Parameter

Finding

Points

age in years

70 to 74 years

0

 

75 to 79 years

1

 

80 to 84 years

2

 

>= 85 years

4

sex

female

0

 

male

1

race

Black

0

 

White

1

eGFR

50 to 59

0

 

40 to 49

1

 

30 to 39

2

 

< 30

4

urine albumin to creatinine ratio

< 30 mg/g

0

 

>= 30 mg/g

1

diabetes

no

0

 

yes

1

smoking

never

0

 

former

1

 

current

2

history of heart failure

no

0

 

yes

2

history of stroke

no

0

 

yes

1

 

total score =

= SUM(points for all 9 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 17

• The risk of mortality increases with the score.

 

Total Score

Risk of 5-Year Mortality

0

3.9%

1

5.9%

2

8.8%

3

13.2%

4

19.4%

5

28%

6

40%

7

54%

8

69%

9

84%

>= 10

94%

 

Performance:

• The area under the ROC curve was 0.69.


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