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Risk Score for Chronic Kidney Disease in General Population

Purpose: To predict the 10-year risk of developing chronic kidney disease using the score of O'Seaghdha et al.

Description

O'Seaghdha et al reported a score for predicting the risk of developing chronic kidney disease in the general population. This was based on data from the Framingham Heart Study and the Atherosclerosis Risk in Communities (ARIC) study. The author are from multiple institutions in Boston and Baltimore.


Patient: adult in the United States from 30 to 85 years of age with eGFR >= 60 mL per min per 1.73 square meters

 

Outcome: chronic kidney disease (CKD) in 10 years

 

Parameters:

(1) age in years

(2) diabetes

(3) hypertension

(4) dipstick for proteinuria (or urine albumin to creatinine ratio)

(5) estimated GFR in mL per min per 1.73 square meters

 

Parameter

Findings

Points

age in years

30 to 34

0

 

35 to 39

1

 

40 to 44

2

 

45 to 49

3

 

50 to 54

4

 

55 to 59

4

 

60 to 64

5

 

65 to 69

6

 

70 to 74

7

 

75 to 79

8

 

80 to 85

9

diabetes

no

0

 

yes

1

hypertension

no

0

 

yes

1

urine protein dipstick

negative

0

 

trace or above

1

eGFR

60 to 74

3

 

75 to 89

1

 

90 to 119

0

 

>= 120

0

 

where:

• A urine albumin to creatinine ratio >= 30 mg/g is an alternate to urine protein dipstick.

 

total score =

= SUM(points for all 5 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 15

• The higher the score the greater the 10-year risk of CKD.

 

Total Score

10-Year Risk

0 or 1

0%

2 or 3

1%

4

2%

5

3%

6

5%

7

9%

8

14%

9

20%

10

30%

11

41%

12

54%

13

66%

14

76%

15

84%

 

Performance:

• The area under the ROC curve is 0.813.


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Specialty

Objective

ICD-10