Sjogren's Syndrome Classification Tree - Medical Algorithm

Description

Vitali et al used a classification tree to evaluate patient's for primary Sjogren's syndrome. The decision points are based on the parameters from the European criteria. The authors are numerous rheumatologists from multiple European countries.

Criteria:

(1) ocular symptoms of dry eyes

(2) oral symptoms of xerostomia

(3) ocular signs (Schirmer or Rose Bengal test)

(4) histopathologic features (focus score)

(5) salivary gland involvement (enlarged salivary glands and/or decreased saliva flow)

(6) presence anti-Ro and/or anti-La

Exclusions:

(1) pre-existing malignant lymphoma

(2) acquired immune deficiency syndrome (AIDS)

(3) sarcoidosis

(4) graft-vs-host disease (GVHD)

Ocular or Oral Symptoms	Ocular Signs	Biopsy (Focus Score)	Salivary Glands Involved	Auto-antibody	Group (End Node)
negative	NA	NA	NA	NA	A
positive	negative	negative	NA	NA	B
positive	negative	positive	negative	NA	C
positive	negative	positive	positive	NA	D
positive	positive	negative	negative	negative	E
positive	positive	negative	positive	negative	F
positive	positive	negative	NA	positive	G
positive	positive	positive	NA	NA	H

Group	Percent of Patient's with Primary Sjogren's	Percent of Normal Controls
A	2%	51%
B	2%	18.9%
C	0.6%	5.6%
D	6%	0%
E	2%	16.7%
F	33%	6.7%
G	4%	0%
H	80%	1%

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Description

Specialty

Objective

ICD-10

Classification Tree of Vitali et al for Primary Sjogren's Syndrome

Purpose: To use the classification tree of Vitali et al to evaluate a patient for Sjogren's syndrome.

Description

Specialty

Objective

ICD-10