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Histologic Grading of a Labial Salivary Gland Biopsy in Patients with Sjogren's Syndrome

Purpose:

To grade a salivary or lacrimal gland for the degree of lymphocytic infiltration in a patient with Sjogren's disease.

Specialty:

Immunology/Rheumatology

Objective:

laboratory tests, severity, prognosis, stage

ICD-10:

M35.0

Description:

Patients with Sjogren's syndrome typically have a chronic inflammatory cell infiltrate of salivary and lacrimal glands. Biopsy of a minor labial salivary gland may be done as part of the diagnostic workup of a patient suspected of having Sjogren's disease. The presence and extent of a lymphocytic infiltrate can be graded by the histopathologist.

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