Criteria of Vitali et al for Sjogren's Syndrome (Preliminary European Criteria)

Has the patient had daily, persistent troublesome dry eyes for more than 3 months?

Does the patient have a recurrent sensation of sand or gravel in the eyes?

Does the patient use tear substitutes more than 3 times a day?

Does the patient have a daily feeling of dry mouth for more than 3 months?

Has the patient had recurrent or persistently swollen salivary glands as an adult?

Does the patient frequently drink liquids to aid swallowing dry foods?

Result of Schirmer-I test

Rose Bengal score (enter from 0 to 9)

Number of inflammatory foci with >= 50 mononuclear cells area of salivary gland tissue

• pre-existing malignant lymphoma?

• acquired immune deficiency syndrome (AIDS)?

• sarcoidosis?

• graft-vs-host disease (GVHD)?

• enlarged salivary glands on scintigraphy?

• evidence of parotid enlargement on parotid sialography?

• unstimulated salivary flow <= 1.5 mL in 15 minutes

• anti-Ro/SS-A?

• anti-La/SS-B?

• ANA?

• rheumatoid factor?