Ten Warning Signs for Primary Immunodeficiency in Children

Is there a family history of a primary immunodeficiency disease?

Has therapy with intravenous antibiotics been required to clear an infection?

Has the patient had persistent thrush in mouth that is unexplained?

Has the patient had persistent fungal infection of skin?

Has the patient failed to grow normally or to gain weight?

Has the patient had recurrent deep skin or organ abscesses?

Number of new ear infections within 1 year

Number of serious sinus infections within 1 year

Number of months of oral antibiotic therapy with little or no effect

Number of episodes of pneumonia within 1 year

Episodes of septicemia or other deep-seated infections