Anti cytokine Autoantibodies | Medical Algorithm

Are you evaluating a patient with unexpected infections?

Yes

Does the patient have infections with?

• Nocardia?

Yes

• Aspergillus?

Yes

• Histoplasmosis?

Yes

• Cryptococcus?

Yes

• Proteus?

Yes

• nontuberculous myobacteria?

Yes

• viral infection?

Yes

• Staphylococcus aureus?

Yes

• mucocutaneous candidiasis?

Yes

• Gram negative infection?

Yes

Can the infections be explained by a known immunodeficiency or immunosuppression?

Yes

Results

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Results Interpretation and Description References Next Steps

Data complete?

Evaluation appropriate?

Number of unexpected pathogens

Should you consider the possibility of anticytokine autoantibodies?

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Risk Factors
- Ten Warning Signs for Primary Immunodeficiency in Children
Clinical Diagnosis, Including Family History For Genetics
- Common Variable Immunodeficiency (CVID)
Laboratory Tests
- When to Suspect the Presence of Anticytokine Autoantibody
Other Testing
- When to Screen Patient for Primary Antibody Deficiency
- Immunocompromising Conditions
Criteria For Diagnosis
Complications
- Definition of Immunosuppression

Monitoring

Complication Detection
- Definition of Immunosuppression

Evaluation

Results

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Monitoring

Specialty

Objective

ICD-10

Anticytokine Autoantibodies | Predisposition to Infection

Purpose: To identify an infection associated with anticytokine autoantibodies.

Evaluation

Results

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Monitoring

Specialty

Objective

ICD-10