Common Variable Immunodeficiency (CVID)

Age of the patient at onset of symptoms

• a history of recurrent and severe bacterial infections?

• a history of recurrent and severe viral infections?

• ITP, autoimmune hemolytic disease, rheumatoid arthritis, pernicious anemia or other autoimmune disease?

• carcinoma and/or malignant lymphoma?

• a sarcoid-like granulomatous inflammation?

• a chronic gastrointestinal disorder?

• splenomegaly?

• chronic lung disease?

• low serum levels of IgG?

• low serum levels in IgA and/or IgM?

• impaired specific antibody response?

Is there another diagnosis that can explain the findings better?