PGA Index for Identifying Alcoholic Liver Disease

Purpose: To estimate the risk of alcoholic liver diseaes based on the simple biological PGA index of Poynard et al.

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Evaluation

Are you evaluating a patient who regularly consumes alcohol?

Yes

Prothrombin time

seconds

Upper limit of reference range for the PT

seconds

Serum GGT

Serum apolipoprotein A-I

Results

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Results Interpretation and Description References Next Steps

Data complete?

Evaluation appropriate?

Total PGA index

Probability of no or minimal disease on liver biopsy

Probability of alcoholic hepatitis or early fibrosis on liver biopsy

Probability of cirrhosis on liver biopsy

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Risk Factors
Clinical Diagnosis, Including Family History For Genetics
Imaging Studies
- Intrahepatic Cholestasis Associated with Alcoholic Liver Disease
Laboratory Tests
Other Testing
Criteria For Diagnosis
- Discriminant Function of Maddrey et al and the Modified Discriminant Function of Carithers et al for Steroid Therapy in Severe Alcoholic Hepatitis
- Criteria for Severe Alcoholic Hepatitis
Severity, Prognosis, Stage
Complications
- Discriminant Function of Maddrey et al and the Modified Discriminant Function of Carithers et al for Steroid Therapy in Severe Alcoholic Hepatitis
Differential Diagnosis And Mimics, Red Flags
- Recognition of Acetaminophen Hepatotoxicity in Chronic Alcoholics
- ANI Model for Evaluating Patient with Steatohepatitis

Therapy

Selection

Monitoring

Disease Progression
- Alcoholic Liver Disease | Combined Clinical & Laboratory Index (CCLI)

Specialty

Gastroenterology
Toxicology

Objective

laboratory tests
other testing
selection

ICD-10

K70.9 - Alcoholic liver disease, unspecified
F10.2 - Mental and behavioural disorders due to use of alcohol, dependence syndrome

Info

Purpose: To estimate the risk of alcoholic liver diseaes based on the simple biological PGA index of Poynard et al.

Specialty: Gastroenterology, Toxicology

Objective: laboratory tests, other testing, selection

ICD-10: K70.9, F10.2,

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