Discriminant Function of Maddrey et al and the Modified Discriminant Function of Carithers et al for Steroid Therapy in Severe Alcoholic Hepatitis

Purpose: To evaluate a patient with alcoholic hepatitis using the discrimant function of Maddrey et al and the modified version by Carithers et al.

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Evaluation

Are you evaluating a patient with alcoholic liver disease?

Yes

Prothrombin time for patient

seconds

Prothrombin time of normal control

seconds

Serum total bilirubin

Results

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Results Interpretation and Description References Next Steps

Data complete?

Evaluation appropriate?

Discriminant function of Maddrey et al

Is the discriminant function elevated?

Modified discriminant function of Carithers et al

Is the modiifed discriminant function elevated?

Is the patient at high risk for short-term mortality if not treated with methylprednisolone?

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Risk Factors
Clinical Diagnosis, Including Family History For Genetics
Imaging Studies
- Intrahepatic Cholestasis Associated with Alcoholic Liver Disease
Laboratory Tests
Other Testing
Criteria For Diagnosis
- Criteria for Severe Alcoholic Hepatitis
Severity, Prognosis, Stage
Differential Diagnosis And Mimics, Red Flags
- Recognition of Acetaminophen Hepatotoxicity in Chronic Alcoholics
- ANI Model for Evaluating Patient with Steatohepatitis

Therapy

Selection

Monitoring

Disease Progression
- Alcoholic Liver Disease | Combined Clinical & Laboratory Index (CCLI)

Specialty

Gastroenterology
Toxicology

Objective

criteria for diagnosis
complications
selection

ICD-10

K70 - Alcoholic liver disease

Info

Purpose: To evaluate a patient with alcoholic hepatitis using the discrimant function of Maddrey et al and the modified version by Carithers et al.

Specialty: Gastroenterology, Toxicology

Objective: criteria for diagnosis, complications, selection

ICD-10: K70,

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