Alcoholic Liver Disease | Step-wise Discriminant Function

 

step-wise discriminant function score =

= (0.21 * (prothrombin time in seconds)) - (0.019 * (hemoglobin as percent normal)) - (0.60 * (albumin in g/dL)) + (1.14 * (encephalopathy score)) + 3.6

 

where:

• prothrombin time = (patient's prothrombin time in second) - (normal control PT in seconds)

• Hemoglobin is expressed as a whole number.

• The "normal" hemoglobin used for calculation is lower limit of reference range; an alternative would be the mean of the reference range.

• The encephalopathy score is 1, 2 or 3.

 

Interpretation

 

Score	% mortality
< -1.1	6%
-1.1 to -0.01	12%
0 - 1.09	20%
1.1 - 2.19	65%
2.2 - 3.29	72%
>= 3.30	100%

 

where:

• The percent mortality is estimated from Figure 5, page 902.