A linear step-wise discriminant function can be used to identify the most important predictors of mortality in alcoholic liver disease.
step-wise discriminant function score =
= (0.21 * (prothrombin time in seconds)) - (0.019 * (hemoglobin as percent normal)) - (0.60 * (albumin in g/dL)) + (1.14 * (encephalopathy score)) + 3.6
• prothrombin time = (patient's prothrombin time in second) - (normal control PT in seconds)
• Hemoglobin is expressed as a whole number.
• The "normal" hemoglobin used for calculation is lower limit of reference range; an alternative would be the mean of the reference range.
• The encephalopathy score is 1, 2 or 3.
-1.1 to -0.01
0 - 1.09
1.1 - 2.19
2.2 - 3.29
• The percent mortality is estimated from Figure 5, page 902.
To read more or access our algorithms and calculators, please log in or register.
Purpose: To evaluate a patient with alcoholic hepatitis using the stepwise discriminant function of Orrego et al.
Specialty: Gastroenterology, Toxicology
Objective: other testing, severity, prognosis, stage