Gedalia et al used a clinical severity score to monitor pediatric patients with sarcoidosis. This can help to determine if a patient is responding to therapy. The authors are from Children’s Hospital and Louisianna State University Medical Center in New Orleans.
Patient selection: pediatric patient with sarcoidosis (biopsy proven, infectious agents excluded)
Parameters:
(1) skin involvement
(2) arthritis (joint involvement)
(3) parenchymal lung involvement with or without hilar lymphadenopathy
(4) bone involvement
(5) iritis/uveitis (eye involvement)
(6) generalized lymphadenopathy and/or splenomegaly
(7) kidney involvement
(8) fever
(9) weight loss
|
Parameter |
Finding |
Points |
|
skin involvement |
absent |
0 |
|
|
present |
2 |
|
joint involvement |
absent |
0 |
|
|
present |
2 |
|
lung involvement |
absent |
0 |
|
|
present |
2 |
|
bone involvement |
absent |
0 |
|
|
present |
2 |
|
eye involvement |
absent |
0 |
|
|
present |
2 |
|
lymphadenopathy/splenomegaly |
absent |
0 |
|
|
present |
2 |
|
kidney involvement |
absent |
0 |
|
|
present |
2 |
|
fever |
absent |
0 |
|
|
present |
1 |
|
weight loss |
absent |
0 |
|
|
present |
1 |
total score =
= SUM(points for all 9 parameters)
Interpretation:
• minimum score: 0
• maximum score: 16
• The higher the score the greater the clinical severity.
• The score could be easily modified to incorporate activity of involvement (mild, moderate, severe).
Purpose: To evaluate a pediatric patient with sarcoidosis using the clinical severity score of Gedalia et al.
Specialty: Immunology/Rheumatology
Objective: severity, prognosis, stage
ICD-10: D86.9,
