Description

D'Amico classified patients with localized prostate cancer into risk groups based on clinical and laboratory findings. The risk group can be helpful in guiding patient management. The authors are from Harvard Medical School, University of Pennsylvania, University of Millersville (Pennsylvania) and Brigham and Women's Hospital.


 

Patient selection: clinically localized prostate cancer (TNM T1c, T2a, T2b, T2c)

 

Parameters:

(1) clinical T stage

(2) serum PSA in ng/mL

(3) Gleason score (Grades 1 and 2)

 

Low risk - all of the following:

(1) T1c or T2a

(2) PSA <= 10 ng/mL

(3) Gleason score <= 6

 

Intermediate risk - any of the following:

(1) T2b

(2) PSA 10.1 to 20 ng/mL

(3) Gleason score 7

 

High risk - any of the following:

(1) T2c

(2) PSA > 20 ng/mL

(3) Gleason score >= 8

 


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