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Initial Dosing in Therapy of Chronic Viral Hepatitis C

Purpose:

To plan the initial dosing of Copegus (ribavirin) and Pegasys (pegylated interferon alfa-2b) for a patient with chronic viral hepatitis C.

Specialty:

Infectious Diseases
Clinical Pharmacology
Gastroenterology

Objective:

pharmacogenetics, dosage calculations

ICD-10:

B18.2

Description:

Chronic viral hepatitis C can be treated using combination therapy with the Copegus formulation of ribavirin (Roche Pharmaceuticals) and Pegasys formulation of pegylated interferon alfa-2b (Roche Pharmaceuticals). Initial dosing is based on the viral genotype and clinical findings in the patient.

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