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Chronic Viral Hepatitis C | Adjusting Dose of Copegus (Ribavirin)

Purpose:

To determine if the dosage regimen of ribavirin (Copegus) given for chronic viral hepatitis C should be adjusted.

Specialty:

Infectious Diseases
Clinical Pharmacology & Toxicology
Gastroenterology

Objective:

pharmacogenetics, dosage adjustments

ICD-10:

B17.1, B18.2

Description:

Hemolytic anemia is a complication of ribavirin therapy. The dose of the Copegus™ formulation of ribavirin (Roche Pharmaceuticals) should be adjusted in the presence of anemia or deterioration in concurrent cardiac or renal disease.

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