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Evaluation

Are you evaluating a patient for sclero-derma involving the skin?

On cooling of an extremity does the patient show?

• pallor?

• cyanosis?

• suffusion?

• objective evidence of delayed recovery after cold challenge?

• abnormal finger systolic pressure (DSP)?

Does the patient show abnormal capillaries on widefield microscopy of the nailfolds?

Does the patient have antibodies with a titer of >= 1:100?

• centromere?

• topoisomerase I?

• fibrillarin?

• PM-Scl?

• fibrillin?

• RNA polymerase I?

• RNA-polymerase III?

Results

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