Description

Kinlin et al developed a clinical rule for predicting nosocomial pneumonia occurring in a patient undergoing coronary artery bypass graft (CABG) surgery. This can help to identify a patient who may benefit from more aggressive management. The authors are from the Hospital for Sick Children in Toronto, University of Toronto, Tenet Healthcare in Dallas and Partners Community Health in Boston.


Parameters:

(1) body weight

(2) residence prior to admission

(3) smoking history

(4) cancer history

(5) chronic obstructive pulmonary diseae (COPD)

(6) history of prior CABG using an internal mammary artery graft (IMAG)

(7) Canadian Cardiovascular Society (CCS) class

(8) serum creatinine

(9) timing of surgery

(10) administration of vancomycin prior to surgery (versus use of cephalosporin)

(11) intraoperative blood transfusion

(12) percutaneous transluminal coronary angioplasty (PTCA) during current hospital stay

(13) ventilation duration in days

 

Parameter

Finding

Points

body weight

normal or obese

0

 

underweight

7

residence prior to admission

residential

0

 

nonresidential

3

smoking history

absent

0

 

present

4

cancer history

absent

0

 

present

4

COPD

absent

0

 

present

3

history of CABG using IMAG

no

0

 

yes

5

CCS class

1 or 2

0

 

3 or 4

2

serum creatinine

<= 1.2 mg/dL

0

 

> 1.2 mg/dL

3

timing of surgery

routine or urgent

0

 

emergent

3

vancomycin prior to surgery

no

0

 

yes

4

intraoperative blood transfusion

no

0

 

yes

2

PTCA during hospital stay

no

0

 

yes

5

ventilation duration

<= 1 day

0

 

> 1 day

11

 

where:

• Nonresidential admission includes an acute care facility, residential or skilled nursing home, rehabilitation facility, etc.

 

total score =

= SUM(points for all of the parameters)

 

X =

= (0.1598 * (score)) – 5.7031

 

probability of nosocomial pneumonia =

= 1 / (1 + EXP((-1) * X))

 

Interpretation:

• minimum score: 0

• maximum score: 56

• The higher the score the greater the risk for a nosocomial pneumonia occurring.

 

Performance:

• The area under the ROC curve was 0.75 to 0.78.


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