Advanced Ovarian Cancer | Score for Predicting Surgical Outcome

 

Patient selection: woman with advanced ovarian cancer

 

Parameters:

(1) omental cake

(2) peritoneal carcinosis

(3) diaphragmatic carcinosis

(4) meseneteric retraction

(5) bowel infiltration

(6) stomach infiltration

(7) liver metastases

Status for Each Parameter	Points
absent	0
present	2

 

predictive index =

= SUM(points for all 7 parameters)

 

Interpretation:

• minimum predictive index: 0

• maximum predictive index: 14

• The higher the score the less likely that the patient will be optimally debulked at surgery.

• The authors selected a predictive index >= 8 for identifying a patient who cannot be optimally debulked.

 

Performance:

• The performance data is given in Table 2 on page 1159.

• The highest Youden score and diagnostic accuracy is for a score >= 4 with a sensitivity of 61% and specificity of 87%.

• A predictive index >= 8 showed 100% specificity (no one "inappropriately unexplored").