Serum CA125 is used in the diagnosis and monitoring of women with epithelial ovarian carcinomas. A prognostic score using the preoperative and postoperative serum CA125 levels correlates with other prognostic features for ovarian neoplasms.
CA125 Serum Concentration
CA125 Serum Score
<= 64 IU/mL
1
65-299 IU/mL
2
>= 300 IU/mL
3
CA125 prognostic score =
= (CA125 serum score preoperative) + (CA125 serum score 1 month postoperative)
Interpretation:
• minimum score: 2
• maximum score: 6
• Women with a prognostic score <=3 have a significantly better prognosis than when the score is >= 4.
CA125 Prognostic Score
Median Survival
2 or 3
approximately 48 months
4, 5 or 6
14.8 months
after Figure 1, page 127
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Purpose: To use the serum CA125 prognostic score to estimate survival in women with malignant epithelial ovarian neoplasms.
Specialty: Hematology Oncology, Surgery, general, Obstetrics & Gynecology
Objective: severity, prognosis, stage
ICD-10: C56,
