Description

The Septic Severity Score was developed by Stevens at the University of Utah in 1983. It is intended to gauge the severity of the multi-organ involvement in a patient with the sepsis syndrome.


Organ systems evaluated:

(1) lung

(2) kidney

(3) coagulation

(4) cardiovascular

(5) liver

(6) gastrointestinal tract

(7) neurologic

 

Point scoring: Abnormal findings assigned a score from 1 to 5 according to the severity of the dysfunction.

 

Organ System

Finding

Points

lung

breathing room air

0

 

oxygen by mask

1

 

intubated. no PEEP

2

 

PEEP, 0-10%

3

 

PEEP > 10% with PaO2 > 50 mm Hg

4

 

maximal PEEP, with PaO2 <= 50 mm Hg

5

kidney

serum creatinine < 1.5 mg/dL

0

 

serum creatinine 1.5 - 2.5 mg/dL

1

 

serum creatinine 2.6 - 3.5 mg/dL

2

 

serum creatinine > 3.6 mg/dl with good urine output (> 50 mL per hour)

3

 

serum creatinine > 3.6 mg/dL with urine volume 20-50 mL per hour

4

 

serum creatinine > 3.6 mg/dL with urine volume < 20 mL per hour

5

coagulation

no ecchymoses and normal coagulation tests

0

 

ecchymoses and normal coagulation tests

1

 

PT 12-14 seconds or PTT 45-65 seconds

2

 

platelet count 20,000 - 100,000 per µL, PT > 14 seconds, PTT > 50 seconds

3

 

platelet count < 20,000 per µL with PT > 14 seconds and PTT > 50 seconds

4

 

evidence of DIC, bleeding

5

cardiovascular

normal

0

 

slight hypotension

1

 

livedo, moderate hypertension

2

 

vasopressors required at moderate doses

3

 

vasopressors required at large doses

4

 

profound hypotension despite maximal vasopressor doses

5

liver

normal liver function tests

0

 

LDH and SGOT increased, bilirubin normal

1

 

bilirubin 1.5 - 2.5 mg/dL

2

 

bilirubin 2.6 - 4.0 mg/dL

3

 

bilirubin 4.1 - 8.0 mg/dL

4

 

precoma with bilirubin > 8.0 mg/dL

5

GI tract

normal

0

 

mild ileus

1

 

moderate ileus

2

 

severe ileus

3

 

bleeding due to erosive gastritis

4

 

mesenteric venous thrombosis

5

neurologic

normal

0

 

obtunded

1

 

disoriented

2

 

irrational

3

 

hyporeactive

4

 

coma

5

after Table page 1191

 

where:

• In Table page 1191, the specifications for the coagulation ratings are a bit vague for ratings 2 and 3 (should these be OR or AND). Also the variability between laboratories for normal ranges of PT and aPTT may not be easily accounted for with the absolute values given for PT and PTT.

• In Table page 1191, the bilirubin for liver rating 3 has an upper limit of 4; for liver rating 4 the lower limit is 4.9.

 

septic severity score =

= ((points for organ with highest score) ^ 2) + ((points for organ with second highest score) ^ 2) + ((points for organ with third highest score) ^ 2)

 

estimated length of stay in survivors in days =

= (0.61 * (septic severity score)) + 12

 

Interpretation:

• minimum score: 0

• maximum score: 75

• The higher the septic severity score, the more severe the sepsis.

• The mean SSS for nonsurvivors was 49, while the mean SSS for survivors was 29. While survivors showed scores from 0 to 60, nonsurvivors had scores > 30.

• Improvement in the score usually correlates with clinical improvement of the patient.


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