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Prognostic Classification of Patients with Septic Shock Based on Cortisol Levels and Cortisol Response to Corticotropin

Purpose:

Purpose: To use cortisol levels before and after corticotropin stimulation to identify patients with septic shock at high risk for short-term mortality.

Specialty:

Emergency Medicine & Critical Care
Emergency Medicine & Critical Care
Infectious Diseases

Objective:

severity, prognosis, stage

ICD-10:

A49.9, R57.2

Description:

Annane et al studied the effect of stress from septic shock on the hypothalamic-pituitary-adrenal axis. They found that the pattern of serum cortisol levels before and after corticotropin stimulation could identify patients with septic shock who were at high risk for death. These patients might benefit from more aggressive or novel therapies.

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