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NAFLD Fibrosis Score

Purpose: To evaluate a patient with non-alcoholic fatty liver disease using the NAFLD Fibrosis Score of Angulo et al.

Description

Angulo et al reported the NAFLD Fibrosis Score for evaluating a patient with non-alcoholic fatty liver disease. This can help to triage a patient for advanced fibrosis. The authors are from Mayo Clinic, University of Sydney, Alma Mater Studiorum University, University of Turin and University of Newcastle


Patient selection: non-alcoholic fatty liver disease

 

Parameters:

(1) age in years

(2) body mass index (BMI) in kg per square meter

(3) impaired fasting glucose (IFG, >= 110 mg/dL) or diabetes

(4) AST to ALT ratio

(5) platelet count in 10^9/L

(6) serum albumin in g/dL

 

Parameter

Finding

Points

age in years

 

0.037 * (age)

BMI

 

0.094 * (BMI)

IFG or diabetes

no

0

 

yes

1.13

AST to ALT ratio

 

0.99 * (ratio)

platelet count

 

-0.013 * (platetet)

albumin

 

-0.66 * (albumin)

 

score =

= SUM(points for all 6 parameters) - 1.675

 

Score

Advanced Fibrosis

> 0.676

present

-1.455 to 0.676

indeterminate

< -1.455

absent

 


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Specialty

Objective

ICD-10