Modified Criteria for Histologic Scoring of Nonalcoholic Steatohepatitis

Purpose: To evaluate a liver biopsy from a patient with nonalcoholic steatohepatitis (NASH) using a modification of the criteria proposed by Lee.

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Evaluation

Are you evaluating a liver biopsy for nonalcoholic steatohepatitis (NASH)?

Yes

Percent of lobular parenchyma showing steatosis (enter from 0 to 100)

percent

Is ballooning degeneration of hepatocytes seen?

Yes

Select the appropriate answer for each histologic finding

Inflammation and/or hepatocyte injury in zone 3 of the hepatic lobule

Fibrosis

Results

Please fill out required fields.

Results Interpretation and Description References Next Steps

Data complete?

Evaluation appropriate?

Does the biopsy meet the criteria for a histologic diagnosis of NASH?

Grade of steatosis

Grade of inflammation

Stage of fibrosis

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Risk Factors
Laboratory Tests
Other Testing
- Grading and Staging Scheme for Nonalcoholic Steatohepatitis
- Pediatric Non Alcoholic Fatty Liver Disease (NAFLD)
Criteria For Diagnosis
- NAFLD Fibrosis Score
Severity, Prognosis, Stage
Complications
- Nonalcoholic Fatty Liver Disease (NAFLD) with Hepatic Fibrosis
Differential Diagnosis And Mimics, Red Flags
- Model for Distinguishing Nonalcoholic Steatohepatitis (NASH) from Cryptogenic Chronic Hepatitis

Therapy

Options
- Predictors of Angulo et al for Hepatic Fibrosis in Patients with Nonalcoholic Steatohepatitis
Prevention
- Predictors of Angulo et al for Hepatic Fibrosis in Patients with Nonalcoholic Steatohepatitis

Monitoring

Disease Progression
- Nonalcoholic Fatty Liver Disease (NAFLD) Activity Score (NAS) of Kleiner et al
Complication Detection
- Nonalcoholic Fatty Liver Disease (NAFLD) with Hepatic Fibrosis

Specialty

Gastroenterology
Nutrition

Objective

risk factors
severity
prognosis
stage
disease progression

ICD-10

K75.8 - Other specified inflammatory liver diseases

Info

Purpose: To evaluate a liver biopsy from a patient with nonalcoholic steatohepatitis (NASH) using a modification of the criteria proposed by Lee.

Specialty: Gastroenterology, Nutrition

Objective: risk factors, severity, prognosis, stage, disease progression

ICD-10: K75.8,

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