Description

Kereiakes et al reported the DAPT (Dual Antiplatelet Therapy) score for patients undergoing percutaneous coronary intervention (PCI). This can help to identify a patient who may benefit from dual antiplatelet therapy. The authors are from multiple institutions in the United States and Europe and belong to the DAPT Study Investigators.


Patient selection: coronary stent placement during PCI

 

DAPT: thienopyridine and aspirin

 

Outcome: bleeding, ischemic event

 

Parameters:

(1) age in years

(2) current cigarette smoker

(3) diabetes mellitus

(4) myocardial infarction at presentation

(5) history of PCI and/or AMI

(6) paclitaxel-eluting stent

(7) stent diameter in mm

(8) CHF or LVEF < 30%

(9) vein graft PCI

 

Parameter

Finding

Points

age in years

< 65 years

0

 

65 to 74.99 years

-1

 

>= 75 years

-2

current cigarette smoker

no

0

 

yes

1

diabetes mellitus

no

0

 

yes

1

AMI at presentation

no

0

 

yes

1

history of PCI or AMI

no

0

 

yes

1

paclitaxel-eluting stent

no

0

 

yes

1

stent diameter

< 3 mm

1

 

>= 3 mm

0

CHF or LVEF < 30%

no

0

 

yes

2

vein graft PCI

no

0

 

yes

2

 

total score =

= SUM(points for all 9 parameters)

 

Interpretation:

minimum score: -2

maximum score: 10

A score < 2 is associated with greater risk of bleeding with a similar risk for ischemia.

A score >= 2 is associated with greater ischemic benefit (lower AMI or stent thrombosis).

A patient with a high DAPT score may benefit from prolonged thienopyridine.


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