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Neuropathy Following Vinca Alkaloid Therapy Clinical Features

Purpose:

To evaluate a patient for evidence of polyneuropathy following therapy with a vinca alkaloid.

Specialty:

Hematology Oncology
Neurology

Objective:

clinical diagnosis, including family history for genetics, complication detection

ICD-10:

G13, C00-C97, C00-D48

Description:

Following therapy with vinca alkaloids a patient may have axonal degeneration in both myelinated and unmyelinated nerve fibers, resulting in a reversible mixed sensori-motor-autonomic polyneuropathy.

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