Jimenez et al reported a simplified version of the Pulmonary Embolism Severity Index (PESI, see 08.29.30). The authors are from a multinational cohort of outpatients registered with the Registro Informatizado de la Enfermedad Tromboembolica (RIETE).
Parameters:
(1) age
(2) history of cancer
(3) history of heart failure and/or chronic lung disease
(4) heart rate
(5) systolic blood pressure
(6) arterial oxyhemoglobin saturation in percent
Parameter
Finding
Points
age
<= 80 years of age
0
> 80 years of age
1
history of cancer
no
0
yes
1
history of heart failure and/or chronic lung disease
no
0
yes
1
heart rate
< 110 beats per minute
0
>= 110 beats per minute
1
systolic blood pressure
>= 100 mm Hg
0
< 100 mm Hg
1
oxygen saturation
>= 90%
0
< 90%
1
simplified PESI =
= SUM(points for all 6 parameters)
Interpretation:
• minimum score: 0
• maximum score: 6
• A score of 0 indicates low risk and a score >= 1 indicates high risk.
Performance:
• The ROC curve for the simplified score was comparable to the original PESI.
• The sensitivity was 96% and specificity 33%. The positive predictive value was 11% and negative predictive value 99% (low false negative, high false positive).
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