Yamanaka et al used a scoring system to grade the severity of postoperative hepatic dysfunction following hepatectomy. The authors are from Hyogo College of Medicine in Japan.
Patient selection: partial hepatectomy for hepatocellular carcinoma
Risk factors for postoperative hepatic failure:
(1) too much removed
(2) too little reserve
Parameters:
(1) stage of hepatic encephalopathy
(2) ascites
(3) hyperammonemia based on blood ammonia
(4) hyperbilirubinemia based on serum total bilirubin
Parameter |
Finding |
Points |
---|---|---|
grade of encephalopathy |
none |
0 |
|
stage I or II |
20 |
|
stage III or IV |
40 |
ascites |
absent |
0 |
|
present |
10 |
serum ammonia |
< 130 µg/dL (normal) |
0 |
|
130 to 180 µg/dL |
10 |
|
> 180 µg/dL (>=1.4 times ULN) |
20 |
serum total bilirubin |
< 1.2 mg/dL (normal) |
0 |
|
1.2 to 6.0 mg/dL |
0 |
|
> 6 mg/dL |
10 * ((value) – 6) |
where:
• Point assignment appears simplistic, using simple multiples.
total score =
= SUM(points for all 4 parameters)
Postoperative mortality was also scored:
Parameter |
Finding |
Points |
---|---|---|
postoperative mortality |
none |
0 |
|
<= 30 days after surgery (1 month) |
100 |
|
> 30 days after surgery |
80 |
Interpretation:
• minimum total score: 0
• maximum total score for survivor: uncertain, may be capped at 60
• maximum total score: 100
Purpose: To determine the severity of postoperative hepatic dysfunction following hepatectomy using the score of Yamanaka et al.
Specialty: Gastroenterology, Surgery, general, Surgery, orthopedic
Objective: severity, prognosis, stage, complications
ICD-10: K76, Z98,