Teh et al evaluated factors affecting mortality following surgery in a patient with cirrhosis. These can help inform a patient and family about the risks associated with surgery and can aid their decision making. The authors are from the Mayo Clinic.
As shown in Figure 1 (page 1264), the short and long-term mortality is comparable for patients with cirrhosis irregardless of whether no surgery, minor surgery or major surgery is performed. Under the best of circumstances mortality at 5 years is around 50%.
Patient selection: ASA class I to IV. ASA V is associated with a very high mortality rate and surgery is usually not advisable.
Parameters:
(1) age in years
(2) preoperative MELD (Model for End-stage Liver Disease) score
(3) ASA classification
Risk increases for:
(1) age > 70 years: equivalent to an additional 3 points to the MELD score
(2) ASA class IV: equivalent to an additional 5.5 points to the MELD score
adjusted MELD score =
= (preoperative MELD score) + (age adjustment) + (ASA class adjustment)
MELD Score |
90 Day Mortality |
---|---|
0 |
2.2% |
5 |
11.5% |
10 |
22.8% |
15 |
35.4% |
20 |
50% |
25 |
65% |
30 |
79.3% |
from Figure 3, page 1267
predicted 90 day mortality =
= (0.02262 * ((MELD)^2)) + (1.932 * (MELD)) + 1.695
Ideal surgical candidate:
(1) < 30 years old
(2) MELD score < 5
(3) ASA class I or II
Additional factors:
(1) Male gender is associated with increased mortality during the first year after surgery.
(2) Emergency surgery does not affect mortality but prolongs hospitalization.
Purpose: To estimate mortality at 90 days following surgery on a patient with cirrhosis based on the model of Teh et al.
Specialty: Gastroenterology, Surgery, general, Surgery, orthopedic
Objective: severity, prognosis, stage
ICD-10: K70.3, K71.7, K74,