MEDPED Criteria - Serum Cholesterol Cut-Offs

Description

Williams et al reported serum levels of cholesterol associated with heterozygous familial hypercholesterolemia at different cur-offs for family history and age. The authors are from the University of Utah. MEDPED is an acronym for Make Early Diagnosis to Prevent Early Death.

Parameters:

(1) serum concentration of total cholesterol or LDL-cholesterol in mg/dL

(2) family history of familial hypercholesterolemia

(3) age in years

If the patient's serum cholesterol or LDL-cholesterol exceeds the cut-off value then the patient should be evaluated for familial heterozygous hypercholesterolemia.

Screening Cutoffs for Total Cholesterol in mg/dL

Age	1st degree relative	2nd degree relative	3rd degree relative	None
<20	220	230	240	270
20-29	240	250	260	290
30-39	270	280	290	340
>=40	290	300	310	360

Screening Cutoffs for LDL Cholesterol in mg/dL

Age	1st degree relative	2nd degree relative	3rd degree relative	None
<20	155	165	170	200
20-29	170	180	285	220
30-39	190	200	210	240
>=40	205	215	225	260

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Description

Specialty

Objective

ICD-10

MEDPED Criteria - Serum Cholesterol Cut-Offs for Familial Heterozygous Hypercholesterolemia

Purpose: To screen a patient for familial heterozygous hypercholesterolemia (FH) based on the serum cholesterol concentration as reported by Williams et al.

Description

Specialty

Objective

ICD-10