Description

VLDL and LDL cholesterol can be estimated in most people by the Friedwald formula.


Specimen: Fasting serum with triglycerides < 400 mg/dL. Fasting is typically "overnight".

 

Friedewald Formulas

 

VLDL cholesterol in mg/dL =

= ((triglycerides in mg/dL) / 5)

 

LDL cholesterol =

= ((total cholesterol in mg/dL) - (VLDL cholesterol in mg/dL) - (HDL cholesterol in mg/dL)) =

= (total cholesterol in mg/dL) - (((triglycerides in mg/dL) / 5) + (HDL cholesterol in mg/dL))

 

NOTE: This assumes that results are in mg/dL. For mmol/L, divide by 2.2 instead of 5.

 

Limitations:

• The calculations are not valid when the triglyceride > 400 mg/dL or if the patient has a type III hyperlipoproteinemia.


To read more or access our algorithms and calculators, please log in or register.