Wallace et al reported preliminary criteria for identifying inactive disease for a patient with Juvenile Idiopathic Arthritis (JIA). The authors are from the University of Washington in Seattle, University of Cincinnati and Pediatria II in Genoa.
Criteria of inactive disease - all of the following:
(1) no evidence of active arthritis in any joint
(2) absence of fever, rash, serositis, splenomegaly or generalized lymphadenopathy due to JIA
(3) no evidence of active uveitis
(4) normal erythrocyte sedimentation rate (ESR) and normal C-reactive protein (CRP)
(5) physician global assessment of disease activity indicated no disease activity
where:
• Active arthritis is defined as a joint with either (a) swelling not due to bony enlargement or (b) limitation in motion with either pain on motion and/or tenderness.
• An isolated finding in a joint (pain on motion, tenderness, limitation in range of motion) can be seen with inactive disease if it is due to trauma or if it is a late residual to past arthritic damage.
Anti-Arthritis and Anti-Uveitis Medication(s)
Number of Months with Inactive Disease
Type of Clinical Remission
one or more
>= 6 months
remission on medication
none
>= 12 months
remission off medication
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