Risk Factors for Overall Survival in Child with Chronic Graft-versus-Host Disease

Purpose: To identify factors impacting survival of a pediatric patient with chronic graft-versus-host disease (GVHD) based on the study of Jacobsohn et al.

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Evaluation

Are you evaluating a pediatric patient with chronic graft-versus-host disease following allogeneic HSCT?

Yes

Age of the patient

years

Was the disease advanced at the time of the transplant?

Yes

Karnofsky status at the time of the transplant

Platelet count at the time of diagnosis of chronic GVHD

Was the graft material derived from the donor's peripheral blood?

Yes

Match status for the donor for transplant

Results

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Results Interpretation and Description References Next Steps

Data complete?

Evaluation appropriate?

Number of risk factors for poor overall survival

Number of risk factors for increased nonrelapse mortality

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Risk Factors
- Chronic GVHD Risk Score
Laboratory Tests
Criteria For Diagnosis
- Chronic Graft vs Host Disease (GVHD) Score
- Criteria for Therapeutic Response for Chronic Graft-versus-Host Disease (GVHD)
Severity, Prognosis, Stage
Complications
- Prognostic Score for Patient with Chronic Graft-versus-Host Disease After Bone Marrow Transplantation

Monitoring

Response To Therapy
Disease Progression
Complication Detection
Comorbid Conditions
- Prognostic Score for Patient with Chronic Graft-versus-Host Disease After Bone Marrow Transplantation

Specialty

Immunology/Rheumatology
Surgery, general

Objective

laboratory tests
disease progression
complication detection

ICD-10

T86 - Failure and rejection of transplanted organs and tissues

Info

Purpose: To identify factors impacting survival of a pediatric patient with chronic graft-versus-host disease (GVHD) based on the study of Jacobsohn et al.

Specialty: Immunology/Rheumatology, Surgery, general

Objective: laboratory tests, disease progression, complication detection

ICD-10: T86,

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