The International Bone Marrow Transplant Registry (IBMTR) modified the Glucksberg scheme for grading acute graft-versus-host disease (GVHD). It is similar to the Glucksberg scheme, but does not use subjective assessment of performance.
IBMTR Index
Criteria
0
• no GVHD (reference population)
A
• Stage 1 skin involvement only
B
• Stage 2 skin involvement only
• Stage 0 - 2 skin involvement with Stage 1-2 liver and/or Stage 1-2 gastrointestinal involvement
C
• Stage 3 skin, liver, and/or gut involvement
D
• Stage 4 skin, liver, and/or gut involvement
Relative Risk for Treatment Failure
95% Confidence Interval
0.85
0.69 - 1.05
1.21
1.02 - 1.43
2.19
1.78 - 2.71
5.69
4.57 - 7.08
where:
• relative risk is based on that seen in the reference population without acute GVHD
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Purpose: To use the IBMTR grading scheme to evaluate a patient with acute graft-versus-host disease (GVHD).
Specialty: Immunology/Rheumatology, Surgery, general
Objective: laboratory tests, disease progression, complication detection
ICD-10: T86,
