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Equation of Rule et al for Estimating the GFR for a Patient with Chronic Kidney Disease from Serum Cystatin C

Purpose: To estimate an adult's glomerular filtration rate (GFR) using the formula of Rule et al based on serum cystatin C.

Description

Rule et al developed a series of equations for estimating the glomerular filtration rate for a patient with chronic kidney disease. Two of these equations are based on the serum cystatin C. The authors are from the Mayo Clinic in Rochester, Minnesota.


Patient selection: adult

 

Parameters:

(1) serum cystatin C in mg/L

 

For a patient with a native kidney:

 

estimated GFR in mL per min per 1.73 square meter BSA =

= 66.8 / ((cystatin C)^1.3)

 

For a patient with a transplanted kidney:

 

estimated GFR in mL per min per 1.73 square meter BSA =

= 76.6 / ((cystatin C)^1.16)


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Specialty

Objective

ICD-10