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Creatinine-Height Index

Purpose: To estimate a patient's muscle mass by comparison of the patient's urinary creatinine output to that of a normal adult.

Description

Excretion of creatinine correlates with muscle mass if renal function, nutrition and diet are normal. In protein-energy malnutrition, there is reduction in total body muscle mass, with a corresponding reduction in 24 hour urinary creatinine excretion.


 

creatinine/height index (CHI) =

= (mg creatinine in 24 hour urine from patient) / (mg creatinine in 24 hour urine from healthy adult control) * 100

 

where:

• The healthy control is of the same sex, age and height.

 

expected 24 hour urine creatinine clearance =

= (ideal body weight in kilograms) * (creatinine coefficient in mg/kg)

 

where:

• For normal adult males, the creatinine coefficient = 23 mg/kg of ideal body weight.

• For women, the creatinine coefficient = 18 mg/kg of ideal body weight.

 

Interpretation:

• Decreases in CHI are proportionate to the decrease in total body muscle mass.

Muscle Mass Depletion

CHI

mild

80-90%

moderate

70-80%

severe

< 70%

 


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Specialty

Objective

ICD-10