The response of a patient with chronic recurrent multifocal osteomyelitis (CRMO) to therapy can be graded by the change in clinical and laboratory findings.
Parameters:
(1) number of bone lesions
(2) clinical signs and symptoms (pain, etc)
(3) serum markers of inflammation
Number of Lesions
Signs and Symptoms
Serum Markers
Response to Therapy
increased
NA
NA
progression
unchanged
worse
NA
progression
unchanged
unchanged
NA
unchanged
fewer and/or smaller
improved
decreased
partial response
none (resolved)
absent
normal
complete response
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